Intra-Uterine Insemination (I.U.I.) involves inserting the male partner’s (or donor’s) prepared semen through the cervix into the uterus, close to the time of ovulation. It is a simpler, less invasive form of fertility treatment. The semen sample is analysed and washed to concentrate the motile sperm. The final prepared sample is used for insemination where it is gently inserted into the uterine cavity using a speculum and a small catheter.

I.U.I. is also used when couples need to use a sperm donor. Donor sperm may be recommended when the male partner has problems with sperm quality or production, including when the sperm is of very poor quality, or if there is a high risk of passing on a genetic disease.